RE:PAIR

Potent bioactive and synergistic Nutraceuticals with antiaging, antioxidant and mitochondria energizing activities.

RE:PAIR is the natural supplement that supports mitochondrial health by reducing oxidative damage and stimulating mitochondria biogenesis. With its powerful antioxidant action, it helps counteract the signs of aging, improves energy and cellular function, and is ideal for the prevention of inflammatory and neurodegenerative diseases.

Format: 60 capsules

Dosage: 2 capsules daily, preferably during or immediately after meals.

Buy Now: Activate your energy potential and protect your skin from the signs of aging. Try it today!

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€30,00
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Composition

RE:PAIR is a highly synergistic formulation that combines natural active ingredients chosen for their complementary properties to optimize the overall effectiveness of the product. Each ingredient was selected not only for its individual benefits, but also for its ability to work in harmony with the others, creating an enhanced effect that improves mitochondrial function, antioxidant action, and overall well-being.

  • Coenzyme Q10 (CoQ10) 200 mg
  • α-lipoic acid 200 mg
  • Chaga fruit extract (Inonotus obliquus) with 25 percent beta-glucans
  • Vitamin E
  • Dihydroquercetin
  • Vitamin B3 (Niacin)
  • Zinc, Manganese, Copper, Selenium
Properties and Efficacy

RE:PAIR is a dietary supplement formulated to stimulate mitochondria biogenesis and protect cells from oxidative damage. Combining natural ingredients and powerful antioxidants, such as CoQ10, α-lipoic acid, and Chaga, RE:PAIR supports mitochondrial renewal, improving energy and cellular vitality. Its anti-aging action affects the skin, cardiovascular and neurological systems, counteracting signs of aging and preventing inflammation-related diseases.

Synergy of components

Coenzyme Q10 (CoQ10) and α-lipoic acid: The antioxidant action of CoQ10 is complemented by that of α-lipoic acid, which restores mitochondrial enzyme activities, improving cellular energy efficiency and protecting cells from oxidative stress.

Chaga fruit extract (Inonotus obliquus): This mushroom brings powerful polyphenols and beta-glucans that further enhance the antioxidant effect, promoting skin protection and strengthening the immune system.

Microelements (Zinc, Manganese, Copper, Selenium): These minerals work in synergy with the other components to support antioxidant enzyme function, enhancing protection against cellular damage and promoting collagen and elastin synthesis.

Vitamins E and B3: The combination of these two vitamins complements the antioxidant action and promotes the maintenance of healthy, supple skin, counteracting signs of aging and improving microcirculation.

Thanks to the balanced and synergistic combination of these ingredients, RE:PAIR is a highly effective supplement that acts in depth, improving cellular health and skin beauty while providing comprehensive support for overall well-being.

Main Benefits
  • Mitochondrial support: Promotes mitochondria biogenesis to enhance cellular energy production.
  • Anti-aging action: Fights oxidative damage and reduces signs of skin aging, improving skin elasticity.
  • Immune system support: Boosts the body's natural defenses through the antioxidant action of Chaga and vitamins.
  • Cardiovascular and neurodegenerative health: Protects the heart and nervous system from degenerative diseases through trace elements and vitamin B3.
Why Choose?

Unique formula: A unique combination of CoQ10, α-lipoic acid and Chaga for synergistic action on cellular and skin well-being.

  • Mitochondrial protection: Helps counteract the slowing of mitochondrial function due to aging, improving vitality and overall health.
  • Comprehensive action: Not only anti-aging, but also support for the immune system, skin, and heart, preventing degenerative diseases.
  • Natural and scientifically supported ingredients: All ingredients are selected for their proven antioxidant and protective properties, supported by scientific research.
Scientific Studies and Insights
  • Coenzyme Q10: Studies have shown that CoQ10 improves mitochondrial function and skin health, reducing signs of aging such as wrinkles and loss of elasticity 
  • α-lipoic acid: Recognized for its powerful antioxidant properties, α-lipoic acid restores mitochondrial activity, protecting cells from oxidative stress and improving energy function 
  • Chaga (Inonotus obliquus): This mushroom contains SOD (Superoxide dismutase), a powerful antioxidant enzyme that helps protect cells from free radical damage and slows skin aging. Clinical studies have shown its effectiveness in reducing UV damage and improving collagen synthesis 
  • Dihydroquercetin: This flavonoid has been studied for its abilities to improve microcirculation, protect the skin and promote collagen and elastin synthesis 
Literature
  1. Blatt, T. & Littarru, G. P. Biochemical rationale and experimental data on the antiaging properties of CoQ(10) at skin level. Biofactors 37, 381-385 (2011).
  2. Marcheggiani, F. et al. Modulation of coenzyme Q(10) content and oxidative status in human dermal !broblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated aging. Aging 11, 2565-2582 (2019).
  3. Podda, M., Zollner, T. M., Grundmann-Kollmann, M., Thiele, J. J., Packer, L., & Kaufmann, R. (2001). Activity of alpha-lipoic acid in the protection against oxidative stress in skin. In Oxidants and antioxidants in cutaneous biology (Vol. 29, pp. 43-51). Karger Publishers.
  4. Ingram, Cass. D.O. Wild Forest Chaga. The King of All Herbs, Mushroom of Immortality. 2010.
  5. Cui, Y., Kim, D. S., & Park, K. C. (2005). Antioxidant effect of Inonotus obliquus. Journal of Ethnopharmacology, 96(1-2), 79-85.
  6. Lee, I. K., Kim, Y. S., Jang, Y. W., Jung, J. Y., & Yun, B. S. (2007). New antioxidant polyphenols from the medicinal mushroom Inonotus obliquus. Bioorganic & Medicinal Chemistry Letters, 17(24), 6678-6681.
  7. Huang, S. Q., Ding, S., & Fan, L. (2012). Antioxidant activities of five polysaccharides from Inonotus obliquus. International Journal of Biological Macromolecules, 50(5), 1183-1187.
  8. Mu, H., Zhang, A., Zhang, W., Cui, G., Wang, S., & Duan, J. (2012). Antioxidative properties of crude polysaccharides from Inonotus obliquus. International Journal of Molecular Sciences, 13(7), 9194-9206.
  9. Yun, J. S., Pahk, J. W., Lee, J. S., Shin, W. C., Lee, S. Y., & Hong, E. K. (2011). Inonotus obliquus protects against oxidative stress-induced apoptosis and premature senescence. Molecules and cells, 31(5), 423-429.
  10. Rodier, F., Zhou, D., & Ferbeyre, G. (2018). Cellular senescence, geroscience, cancer and beyond. Aging (Albany NY), 10(9), 2233.
  11. Smallwood MJ, Nissim A, Knight AR et al (2018) Oxidative stress in autoimmune rheumatic diseases. Free Radic Biol Med 125:3-14 
  12. Nounou HA, Deif MM, Arafah M (2010) The influence of dex- amethasone and the role of some antioxidant vitamins in the pathogenesis of experimental bronchial asthma. J Exp Pharmacol 2:93-103 
  13. Lee KH, Jeong D (2012) Bimodal actions of selenium essential for antioxidant and toxic pro-oxidant activities: the selenium paradox (review). Mol Med Rep 5:299-304 
  14. Harris, E. D. (2001). Copper homeostasis: the role of cellular transporters. Nutrition reviews, 59(9), 281-285.
  15. Gropper, S. S., Smith, J. L., & Groff, J. L. (2013). Advanced nutrition and human metabolism 6th ed. USA: Wardsworth Cengage Learning.
  16. Roohani, N., Hurrell, R., Kelishadi, R., & Schulin, R. (2013). Zinc and its importance for human health: An integrative review. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences, 18(2), 144.
  17. Wołonciej, M., Milewska, E., & Roszkowska-Jakimiec, W. (2016). Trace elements as an activator of antioxidant enzymes. Postepy higieny i medycyny doswiadczalnej (Online), 70, 1483-1498.
  18. Boissy, R.E., Minwalla, L., Bissett, D.L., Zhuang, J.C., and Chhoa, M., Niacinamide inhibits transfer of melanosomes from melanocytes to keratinocytes, 59th Annu- al Meeting American Academy of Derma- tology, Washington, DC, 2001. 
  19. Biedermann,K., Lammers,K. ,Mrowczynski, E., Coombs, M., Lepp, C., El-Nokaly, M., and Burton, E., Regulation of sebum production by niacinamide, 60th Annual Meeting American Academy of Derma- tology, New Orleans, 2002. 
  20. Matts, P. J., Oblong, J. E., & Bissett, D. L. (2002). A review of the range of effects of niacinamide in human skin. IFSCC Magazine, 5(4), 285-289.
  21. Pehr, K., & Forsey, R. R. (1993). Why don't we use vitamin E in dermatology?. CMAJ: Canadian Medical Association Journal, 149(9), 1247.
  22. Weidmann, A. E. (2012). Dihydroquercetin: More than just an impurity?. European journal of pharmacology, 684(1-3), 19-26.

About Us

Kiros Diet

We offer high quality natural food supplements and phytoterapics products based on 25 years of research and clinical studies.

Our supplements: with the right vitamins, natural substances and herbal extracts, we can now optimize mental and physical energy, support immune system, improve quality of life in the long term, and so much more. The supplements developed by our team offer the highest level of safety and efficiency.

How Kiros Diet supplements come about
From the collaboration between Prof. Giuseppe Castaldo and Prof. Luca Rastrelli of the Department of Pharmacy at the University of Salerno, an internationally renowned center of excellence in the field of nutritional supplements and nutraceuticals research.

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