DE:TOX

The combination of Polyporus umbellatus, Orthosiphon, Dandelion, Hawthorn, Silymarin, Quercetin, and Chromium offers powerful draining, purifying, and antioxidant action, improving overall health and well-being of the body, reducing water retention, and stimulating metabolism.

Each Kiros De:tox tablet provides:

• Polyporus umbellatus (mushroom), extract titrated to 30% polysaccharides - 200 mg
• Orthosiphon stamineus (Java tea) - 200 mg
• Dandelion (Root) - 140 mg
• Hawthorn (Crataegus oxyacantha) - 100 mg
• Silymarin (milk thistle extract) - 100 mg
• Sophora japonica 10 mg with 9.8 mg quercetin
• Chromium - 40 mcg

Kiros De:tox is the ideal solution for those who want support in the fight against cellulite and those who suffer from water retention. Its unique formula works effectively by stimulating the drainage of excess fluids and improving microcirculation, two key factors in combating the formation of cellulite.

Polyporus umbellatus, a mushroom with roots in Traditional Chinese Medicine, is the main active ingredient in this formula, known for its natural diuretic properties that help eliminate excess fluids, stimulating the excretion of sodium and chlorine without compromising potassium balance, preserving muscle tone. Essential for muscle and nerve health In addition, the mushroom stimulates immunity, promoting purification of the body.

Synergistically, extracts of Orthosiphon (Java Tea), Dandelion, Hawthorn, Silymarin, and Chromium work together to improve vein wall elasticity, reduce capillary permeability, and promote proper function of the lymphatic system. These ingredients are particularly useful in the treatment of cellulite, as they improve skin tone and elasticity, counteract fluid stagnation, and support the purification process.

Quercetin, a potent flavonoid, helps fight oxidative stress and improve vascular wall health by promoting blood and lymphatic circulation. This further contributes to the reduction of water retention and the fight against cellulite.

Kiros De:tox is ideal for those seeking to:

• Reduce water retention and swelling (edema)
• Combat cellulite and improve the appearance of the skin, making it firmer and smoother
• Stimulate diuresis naturally, without loss of potassium
• Promote the body's purification process and detoxification
• Supporting liver and cardiovascular function
• Improve the health of the lymphatic system and microcirculation

Kiros De:tox is the ideal treatment for those suffering from water retention and cellulite. The powerful draining action of Polyporus umbellatus, combined with the benefits of Orthosiphon, Dandelion, Hawthorn, Silymarin, Chromium, and Quercetin, helps to improve skin elasticity and tone, reduce swelling, and support a complete purification of the body. In addition, Chromium stimulates metabolism, making Kiros De:tox a perfect ally during restrictive diets and to improve weight control. A safe, natural and complete supplement for those who want to fight cellulite and improve overall well-being.

• Polyporus umbellatus (mushroom): This mushroom has a powerful diuretic action that stimulates fluid excretion without loss of potassium, which is essential for muscle health. It is also an immunostimulant, promoting purification of the body and helping to reduce excess fluids.
• Orthosiphon stamineus (Java tea): Known for its diuretic properties, this extract promotes the elimination of excess fluids and helps improve microcirculation, which is essential for fighting cellulite and bloating.
• Dandelion (Root): Stimulates biliary, hepatic and renal function, promoting the elimination of toxins and improving tissue elasticity. It is particularly useful in combating water retention and cellulite.
• Hawthorn (Crataegus oxyacantha): Known for its cardiotonic properties, hawthorn improves blood and venous circulation, fighting fluid stagnation and promoting cardiovascular health.
• Silymarin (Milk Thistle): Powerful antioxidant that supports liver health, enhancing body detoxification and promoting overall well-being.
• Chromium: Helps improve carbohydrate metabolism and stimulate insulin sensitivity, supporting weight control and fluid balance in the body.
• Quercetin: Flavonoid with antioxidant properties that helps improve vascular wall health, promoting blood and lymphatic circulation and reducing water retention.

1. Huang, P. L. (2009). A comprehensive definition for metabolic syndrome. Disease models & mechanisms, 2(5-6), 231-237.12 Kobayashi M, Matsui-Yuasa I, Fukuda-Shimizu M, Mandai. 
2. Zhao, Y. Y. (2013). Traditional uses, phytochemistry, pharmacology, pharmacokinetics and quality control of Polyporus umbellatus (Pers.) Fries: a review. Journal of ethnopharmacology, 149(1), 35-48.
3. Zhao, Y. Y., Xie, R. M., Chao, X., Zhang, Y., Lin, R. C., & Sun, W. J. (2009). Bioactivity-directed isolation, identification of diuretic compounds from Polyporus umbellatus. Journal of ethnopharmacology, 126(1), 184-187. 
4. Dai, H., Han, X. Q., Gong, F. Y., Dong, H., Tu, P. F., & Gao, X. M. (2012). Structure elucidation and immunological function analysis of a novel β-glucan from the fruit bodies of Polyporus umbellatus (Pers.) Fries. Glycobiology, 22(12), 1673-1683.
5. Adam, Y., Somchit, M. N., Sulaiman, M. R., Nasaruddin, A. A., Zuraini, A., Bustamam, A. A., & Zakaria, Z. A. (2009). Diuretic properties of Orthosiphon stamineus Benth. Journal of Ethnopharmacology, 124(1), 154-158.
6. Singh, M. K., Gidwani, B., Gupta, A., Dhongade, H., Kashyap, P. P., & Tripathi, D. K. (2015). A review of the medicinal plants of genus Orthosiphon (Lamiaceae). Int J Biol Chem, 9, 318-31.
7. Seyedan, A., Alshawsh, M. A., Alshagga, M. A., & Mohamed, Z. (2017). Antiobesity and lipid lowering effects of Orthosiphon stamineus in high-fat diet-induced obese mice. Planta medica, 83(08), 684-692.
8. Choi, U. K., Lee, O. H., Yim, J. H., Cho, C. W., Rhee, Y. K., Lim, S. I., & Kim, Y. C. (2010). Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits. International journal of molecular sciences, 11(1), 67-78.
9. Choi, U. K., Lee, O. H., Yim, J. H., Cho, C. W., Rhee, Y. K., Lim, S. I., & Kim, Y. C. (2010). Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits. International journal of molecular sciences, 11(1), 67-78.
10. Orhan, I. E. (2018). Phytochemical and pharmacological activity profile of Crataegus oxyacantha L.(hawthorn)-A cardiotonic herb. Current medicinal chemistry, 25(37), 4854-4865.
11. Bahmani, M., Shirzad, H., Rafieian, S., & Rafieian-Kopaei, M. (2015). Silybum marianum: beyond hepatoprotection. Journal of evidence-based complementary & alternative medicine, 20(4), 292-301.
12. Freitag, A. F., Cardia, G. F. E., da Rocha, B. A., Aguiar, R. P., Silva-Comar, F. M. D. S., Spironello, R. A., ... & Cuman, R. K. N. (2015). Hepatoprotective effect of silymarin (Silybum marianum) on hepatotoxicity induced by acetaminophen in spontaneously hypertensive rats. Evidence-Based Complementary and Alternative Medicine, 2015.
13. Svobodová, A., Zdařilová, A., Mališková, J., Mikulková, H., Walterová, D., & Vostalová, J. (2007). Attenuation of UVA-induced damage to human keratinocytes by silymarin. Journal of Dermatological Science, 46 (1), 21-30.
14. Sala, M., Breithaupt, L., Bulik, C. M., Hamer, R. M., La Via, M. C., & Brownley, K. A. (2017). A double-blind, randomized pilot trial of chromium picolinate for overweight individuals with binge-eating disorder: effects on glucose regulation. Journal of dietary supplements, 14(2), 191-199.
15. Orhan, C., Kucuk, O., Tuzcu, M., Sahin, N., Komorowski, J. R., & Sahin, K. (2019). Effect of supplementing chromium histidinate and picolinate complexes along with biotin on insulin sensitivity and related metabolic indices in rats fed a high-fat diet. Food science & nutrition, 7(1), 183-194.
16. Long, X., Zeng, X., Zhang, F. Q., & Wang, X. J. (2006). Influence of quercetin and x-ray on collagen synthesis of cultured human keloid-derived fibroblasts. Chinese medical sciences journal, 21(3), 179-183.
17. Gopalakrishnan, A., Ram, M., Kumawat, S., Tandan, S. K., & Kumar, D. (2016). Quercetin accelerated cutaneous wound healing in rats by increasing levels of VEGF and TGF-β1. NISCAIR Online Periodicals Repository, 187-195